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最近更新于 2021-11-17.

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周鹏

基因的表达是如何受到调控,同时又是如何影响植物表型的?我希望结合传统遗传学、比较基因组学和多组学数据挖掘等手段,以玉米和小麦为模型研究作物在生长发育过程和胁迫条件下的基因表达调控机制,鉴定关键的顺式调控元件和反式作用因子用于作物改良。此外,我将借助大数据分析和多组学数据整合构建植物基因调控网络,训练机器学习模型用于预测基因的时空特异性表达模式,对作物进行精准育种和设计。欢迎对生信感兴趣的同学加入我们团队!

教育背景

博士:植物病理学&生物信息学

明尼苏达大学双城分校

圣保罗,美国

2015 - 2009

  • 导师:Nevin D Young

硕士:法医遗传学

西安交通大学

中国,西安

2009 - 2007

  • 导师:李生斌

学士:生物工程&计算机科学

西安交通大学

中国,西安

2007 - 2003

研究经历

研究员

作物生物信息学

中国农业科学院作物科学研究所,北京

至今 - 2021

博士后

植物与微生物学系

明尼苏达大学双城分校

2021 - 2016

  • 导师:Nathan M Springer

农业信息分析师

应用经济系

明尼苏达超级计算中心

2016 - 2015

研究助理

植物病理系

明尼苏达大学双城分校

2015 - 2009

代表性著作

Prediction of conserved and variable heat and cold stress response in maize using cis-regulatory information

Plant Cell. 2021. doi:10.1093/plcell/koab267

N/A

2021

  • Zhou P, Enders TA, Myers ZA, Magnusson E, Crisp PA, Noshay J, et al.
  • Impact Factor = 11.277

Meta Gene Regulatory Networks in Maize Highlight Functionally Relevant Regulatory Interactions

Plant Cell. 2020, 32: 1377-1396.

N/A

2020

  • Zhou P, Li Z, Magnusson E, Cano FAG, Crisp PA, Noshay J, Grotewold E, HirschC, Briggs SP, Springer NM
  • Impact Factor = 11.277

Dynamic Patterns of Gene Expression Additivity and Regulatory Variation throughout Maize Development

Molecular Plant. 2019, 12: 410-425.

N/A

2019

  • Zhou P, Hirsch CN, Briggs SP, Springer NM
  • Impact Factor = 10.812

Strategies for optimizing BioNano and Dovetail explored through a second reference quality assembly for the legume model

BMC Genomics. 2017, 18: 578.

N/A

2017

  • Moll KM*, Zhou P*, Ramaraj T, Fajardo D, Devitt NP, Sadowsky MJ, et al

Exploring structural variation and gene family architecture with De Novo assemblies of 15 Medicago genomes

BMC Genomics. 2017, 18: 261.

N/A

  • Zhou P, Silverstein KAT, Ramaraj T, Guhlin J, Denny R, Liu J, et al

其他著作

  • Citation = 2372
  • H-index = 17
  • I10-index = 20

Plant height heterosis is quantitatively associated with expression levels of plastid ribosomal proteins

Proc Natl Acad Sci U S A.. 2021. doi: 10.1073/pnas.2109332118

N/A

2021

  • Birdseye D, de Boer LA, Bai H, Zhou P, Shen Z, Schmelz EA, Springer NM, Briggs SP

Widespread imprinting of transposable elements and young genes in the maize endosperm

PLoS Genetics. 2021;17: e1009491.

N/A

  • Anderson SN, Zhou P, Higgins K, Brandvain Y, Springer NM

Assessing the regulatory potential of transposable elements using chromatin accessibility profiles of maize transposons

Genetics. 2021, 217: 1–13.

N/A

  • Noshay JM, Marand AP, Anderson SN, Zhou P, Guerra MKM, Lu Z, et al

Single-parent expression drives dynamic gene expression complementation in maize hybrids

Plant Journal. 2021, 105: 93–107.

N/A

  • Li Z, Zhou P, Della Coletta R, Zhang T, Brohammer AB, H O’Connor C, et al.

The antagonistic MYB paralogs RH1 and RH2 govern anthocyanin leaf markings in Medicago truncatula

New Phytologist. 2021, 229: 3330–3344.

N/A

  • Wang C, Ji W, Liu Y, Zhou P, Meng Y, Zhang P, et al.

Stable unmethylated DNA demarcates expressed genes and their cis-regulatory space in plant genomes

Proc Natl Acad Sci U S A.. 2020, 117: 23991–24000.

N/A

2020

  • Crisp PA, Marand AP, Noshay JM, Zhou P, Lu Z, Schmitz RJ, et al.

Variation and Inheritance of Small RNAs in Maize Inbreds and F1 Hybrids

Plant Physiol. 2020, 182: 318-331.

N/A

  • Crisp PA, Hammond R, Zhou P, Vaillancourt B, Lipzen A, Daum C, et al

Monitoring the interplay between transposable element families and DNA methylation in maize

PLoS Genetics. 2019, 15: e1008291.

N/A

2019

  • Noshay JM, Anderson SN, Zhou P, Ji L, Ricci W, Lu Z, et al

Transposable elements contribute to dynamic genome content in maize

Plant Journal. 2019, 100: 1052-1065.

N/A

  • Anderson SN, Stitzer MC, Brohammer AB, Zhou P, Noshay JM, O’Connor CH, et al

Hybrid assembly with long and short reads improves discovery of gene family expansions

BMC Genomics. 2017, 18: 541.

N/A

2017

  • Miller JR, Zhou P, Mudge J, Gurtowski J, Lee H, Ramaraj T, et al

Exploring structural variants in environmentally sensitive gene families

Curr Opin Plant Biol. 2016, 30: 19–24.

N/A

2016

  • Young ND, Zhou P, Silverstein KA

Genomic signature of adaptation to climate in Medicago truncatula

Genetics. 2014, 196: 1263–1275.

N/A

2014

  • Yoder JB, Stanton-Geddes J, Zhou P, Briskine R, Young ND, Tiffin P

Selection, genome-wide fitness effects and evolutionary rates in the model legume Medicago truncatula

Molecular Ecology. 2011, 108: E864-70.

N/A

2013

  • Paape T, Bataillon T, Zhou P, J Y Kono T, Briskine R, Young ND, et al

Detecting small plant peptides using SPADA (Small Peptide Alignment Discovery Application)

BMC Bioinformatics. 2013, 14: 335.

N/A

  • Zhou P, Silverstein KA, Gao L, Walton JD, Nallu S, Guhlin J, et al

Whole-genome nucleotide diversity, recombination, and linkage disequilibrium in the model legume Medicago truncatula

Proc Natl Acad Sci U S A. 2013, 22: 3525–3538.

N/A

  • Branca A, Paape TD, Zhou P, Briskine R, Farmer AD, Mudge J, et al

Fine-scale population recombination rates, hotspots, and correlates of recombination in the Medicago truncatula genome)

Genome Biol Evol. 2012, 4: 726–737.

N/A

2012

  • Paape T, Zhou P, Branca A, Briskine R, Young N, Tiffin P

The Medicago genome provides insight into the evolution of rhizobial symbioses

Nature. 2011, 480: 520-524.

N/A

2011

  • Young ND, Debellé F, Oldroyd GED, … , Zhou P, …, et al
  • ESI Highly Cited Paper

职业经历

杂志审稿人

N/A

N/A

  • Plant Biotechnology Journal
  • Plant Science
  • The Plant Genome
  • Plant Direct
  • Crop Science

大会经历

Meta gene regulatory networks in maize refine functionally relevant regulatory interactions

Plant and Animal Genome XXVIII Conference

圣地亚哥

2020

Exploring Functional Transcriptomics using Gene Regulatory Networks in Maize.

61st Annual Maize Genetics Conference

圣路易斯

2019

Documenting the Manifestations of Heterosis in Co-expression Networks for Maize

Plant and Animal Genome XXVI Conference

圣地亚哥

2018

The Medicago Pan-Genome Reveals Large-scale Variation

Plant and Animal Genome XXII Conference

圣地亚哥

2014

Detecting secreted peptides in plants using SPADA (Secreted Peptide Alignment Discovery Algorithm)

Plant and Animal Genome XXI Conference

圣地亚哥

2013

Population-Scale Deep Sequencing Reveals Extensive Structural Variation in Medicago species

Minnesota Supercomputing Institute Research Exhibition

明尼阿波利斯

2011

Genome Distribution and Population Genetics of Nodule-Specific Cysteine-Rich (NCR) Peptides in Medicago

Plant and Animal Genome XIX Conference

圣地亚哥

A Medicago truncatula Hapmap as a Platform for Exploring the Genetics of Symbiosis

Plant and Animal Genome XVIII Conference

圣地亚哥

2010

应邀报告

Co-expression based Gene Regulatory Networks Predict Functional Interactions in Maize

N/A

中国农业大学,北京

2019

Transcriptome Dynamics in Maize

N/A

华中农业大学,武汉

Toward a Medicago Pan-genome: Assembling and Comparing Multiple Genomes

Medicago truncatula Workshop

Noble Research Institute, Ardmore

2016

Assembling and Comparing Multiple High-Quality Medicago Genomes

N/A

中国农业科学院,北京